Despite dominating possession throughout, Barcelona's feted front three of Lionel Messi, Suarez and Neymar were sluggish before the break, misplacing passes and failing to register a shot on target.
The visitors were gifted the lead, however, when ex-Watford midfielder Jurado tried to curve a pass back to Lopez with the outside of his foot, contriving only to give Suarez a free run on goal.
That mistake compounded an earlier one from Jurado, who dragged an effort well wide when through on goal as the hosts split the Barcelona defence apart on five minutes, in what proved to be their best chance of the game.
Even after Suarez's opener, Espanyol held firm against their neighbours until Messi carved them apart with a surging run on 76 minutes, rolling the ball to Rakitic for a simple finish.
Espanyol left-back Aaron Martin then produced a horrid mis-kick when attempting to clear a cross, allowing Suarez to score his 26th league goal of the season.
