Roberto will most likely miss the match due to the Knock he got.
He has yet to play in a Copa match so far this season, He got that Groin Injury vs Bate and was out for 10 days and missed the first leg vs Villanovense. and during the Roma 2nd Leg CL match he got tackled hard and hurt his Ankle, and he missed the Second leg vs Vilanovense.
With him getting a Knock from the match vs Espanyol he will most likely miss his third straight Copa Match.