I prefer for Iniesta to be rested ahead of the derby on Saturday (even that this would probably mean Gomez in the starting eleven). If we can't win with 3+ difference against poor Osasuna without him, then why bother at all.
But I expect a heavy beat to Osasuna tomorrow. The determination should be huge after the win on Sunday, Messi on fire, finally time for Suarez to find the net couple of times, maybe a goal or two from Paco to boost his confidence a bit (before being stuck on the bench again for the rest of the season when Neymar comes back
)