As a Unit I still think the best would be one ball dependent,2 less
1-Messi-Villa-Pedro
2-Alexis-Villa-Pedro
then you can have
3-Messi-Alexis-Villa
4-Messi-Alexis-Pedro
I know this would shock many but think ALexis-Villa-Pedro would work better than Messi-Alexis-Pedro/VIlla for example
we will see....
But there should be plenty of rotation to keep everyone fresh. Even Messi can sit some matches, a trident of Pedro, Sanchez and Villa can get the job done and allow Messi to enjoy some much needed rest.
Sanchez arrival should only mean there are more rotating options. So I expect him to share playing time with MVP equally once he has integrated into our system.
But if we reach the UCL final again, with a fully fit squad, sorry Sanchez, but MVP should get the nod.