Panthers are the favorites and they should win but you cannot count out the Broncos and in fact I expect a very tight and competitive game.
The keys of the game are basically can the Panthers continue to limit pressure and protect Cam as well as they have been doing all season now facing the league's best defense. And can Manning limit turnovers to keep the score low and give his defense a fighting chance.
If the Broncos can pressure on defense and limit TO on offense, they'll be in this game.