Alexis top 2 qualities are his tireless work rate and creativity. To maximize this, IMO they should drop Alexis deeper and a little more centrally. Get him away from the right corner where he often gets trapped and does not have the dribbling skills in tight spaces to get out.
This would mean less scoring for Alexis, but hopefully more assists. For this to happen though, the team either needs Neymar to get much better at finishing, or to go and find a nice mobile 9. Then with the 9, Lucho would have to be clever with his rotations and formations to get them in the best of positions and get them all minutes.
They might, might, want to experiment with Alexis in a free role as the furthest man of the field, however when opponents park the bus IMO Alexis simply does not have the close control in tight spaces for that to be efficient.
IMO his very best position for this team is a deeper one where he can see more of the ball and where his creativity and workrate can create some problems for defenses and where his poor control under pressure and in tight spaces can be less of a problem.