Pedro would play on right wing, but if we were to play without both Ronaldo and Higuain we would be extremely lucky to come away with any positive result from Mestalla, that includes a draw considering the morale and the formation still in pieces and worsened by injuries. It's going to be very hard for us to score unless Di Maria, Ozil and Benzema step it up.
I don't believe that Ronaldo will be out for Valencia, but I still think we need a canterano to join the squad to replace injured Higgy.
Mido, these wouldn't make sense at all. Granero is being played as a box-to-box midfielder more often these days playing next to a CM. Leon can't be the one to rely on in terms of scoring, even though he deserves to feel that he is needed in the team. Ozil is the source of our attacking creativity and we need him to play wherever he is comfortable.
And Pepe ? He has learned how to handle the pressure and becomes more professional each time we see him. He might still be considered a douchebag and an animal, but he becomes the Carvalho type of CB. He is more agressive, more confident and has much more self-belief, he makes successful tackles much more often than earlier. He is a very good player and I think he wouldn't do as bad against opposition any other than Barca if he and his partners supported each other properly.