some of the effects of ghd that appear in adulthood i was reading about
Reduced muscle mass and strength
Reduced bone mass and osteoporosis
Reduced quality of life, particularly energy levels
Cardiac dysfunction, including a thickened intima media
Increased body fat, particularly around the waistline
Interesting... However I can tell you from first hand experience that not all of those may happen... My dad had a growth problem in his youth and had a hormone treatment, probably not as good as Messi's and he finally reached 1.71 meters tall (around 5' 6")... My dad has had an athlete's life, he's has played sports (football, tennis, basketball, volleyball) all his life, some of them at national level, and he's is very careful with his food, doesn't smoke and doesn't drink... Right now he is 57 and his health is perfect, the only of those symptoms that you mention that he has is the reduced bone mass, because during the growth treatment bones are not able to hold as much calcium as they should or something like that, yet he's built like a tree and doesn't have any problem playing football with players with 30 years less (he used to play with us in some tournament and he could still hold it without any problem, sometimes he even kicked our asses, hahaha)... So yeah, Messi's plays in whole different level but he also gets taken care of a lot much better, so I don't think we need to worry about his body breaking or something like that...